Dr. Wilson as a student studied the control of urinary acid secretion by adrenal hormones as as a resident investigated cholesterol metabolism. At the NIH he studied ethanolamine biosynthesis, since 1960 he has been in the Department of Internal Medicine at UT Southwestern. In 1970 he worked at Cambridge University, and he has collaborated since 1985 with Marilyn B. Renfree in Melbourne investigating sexual differentiation in marsupials. His research has focused on two problems. The cholesterol project (1960-72)developed methods for quantification of cholesterol synthesis, absorption, degradation, and excretion in intact animals. Demonstration that plasma cholesterol is synthesized in the intestinal wall and liver led to development of paradigms to define the contributions of diet and endogenous synthesis to cholesterol turnover in humans and baboons. <snip>
and model Ruby Jean Wilson
